Lilly (LLY) Q4 2025 Financial Results Summary
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Eli Lilly and Company (LLY) Q4 2025 Financial Results Summary
Eli Lilly and Company (NYSE: LLY) released its financial results for the fourth quarter of 2025 on February 4, 2026. Here’s a summary of the key highlights from the report:
Financial Highlights
- Revenue: Increased by 43% to $19.3 billion from $13.5 billion in Q4 2024.
- Net Income (Reported): Grew by 50%, reaching $6.6 billion compared to $4.4 billion in Q4 2024.
- Earnings Per Share (EPS):
- Reported EPS increased by 51% to $7.39 from $4.88 a year earlier.
- Non-GAAP EPS rose 42% to $7.54 from $5.32 in Q4 2024.
- Gross Margin: Increased by 43% to $15.9 billion, with a gross margin percentage of 82.5%, up 0.3 percentage points compared to Q4 2024.
Segment Performance
- U.S. Revenue: Up 43% to $12.9 billion, driven by a 50% increase in sales volume, despite a 7% decrease due to lower realized prices.
- International Revenue: Rose 43% to $6.4 billion, with a 38% volume increase and a 4% favorable impact from foreign exchange rates.
Product Performance
- Mounjaro:
- Q4 2025 revenue increased by 110% to $7.4 billion, with U.S. revenue climbing 57% to $4.1 billion.
- Zepbound:
- U.S. revenue surged by 122% to $4.2 billion, up from $1.9 billion in Q4 2024.
- Verzenio:
- Worldwide revenue grew by 3% to $1.6 billion, with U.S. revenue declining by 4% but international sales increased by 18%.
Costs and Expenses
- Research and Development (R&D): Increased by 26% to $3.8 billion, accounting for 20% of revenue.
- Marketing, Selling, and Administrative Expenses: Rose by 29% to $3.1 billion, reflecting increased promotional efforts.
Tax and Effective Tax Rate
- Effective Tax Rate: Increased to 19.7% compared to 12.5% in Q4 2024, largely due to a less favorable jurisdictional mix of earnings and changes in U.S. tax laws.
Guidance for 2026
- Revenue Guidance: Expected between $80 billion to $83 billion.
- Non-GAAP EPS Guidance: Expected in the range of $33.50 to $35.00.
Dividends and Share Repurchase
- Quarterly Dividend: Declared at $1.50 per share, representing a 15% increase from $1.30 per share in Q4 2024.
Regulatory and Pipeline Updates
- Regulatory Advances:
- FDA approval of Kwikpen for tirzepatide and expanded indication for Jaypirca.
-
Submissions for orforglipron for obesity to regulatory authorities in the U.S., Japan, and in the EU for both obesity and type 2 diabetes.
-
Pipeline Developments:
- Positive Phase 3 results for multiple products and partnerships aimed at expanding access to obesity medicines.
Summary of Financial Results in Bullets
- Q4 2025 Revenue: $19.3 billion (Up 43%)
- Net Income (Reported): $6.6 billion (Up 50%)
- Reported EPS: $7.39 (Up 51%)
- Non-GAAP EPS: $7.54 (Up 42%)
- Gross Margin: $15.9 billion (Up 43%); Margin %: 82.5% (Up 0.3%)
- U.S. Revenue: $12.9 billion (Up 43%)
- International Revenue: $6.4 billion (Up 43%)
- Research and Development Expenses: $3.8 billion (Up 26%)
- Marketing and Administrative Expenses: $3.1 billion (Up 29%)
- Effective Tax Rate: 19.7% (vs 12.5% in Q4 2024)
- 2026 Revenue Guidance: $80 – $83 billion
- 2026 Non-GAAP EPS Guidance: $33.50 – $35.00
- Q4 2025 Dividend: $1.50 per share (Up 15%)
Eli Lilly continues to demonstrate robust growth and operational advancements, positioning itself favorably for the upcoming year.
CONDENSED CONSOLIDATED STATEMENTS OF INCOME
| $ in millions, except | Fourth-Quarter | 2025 | 2024 | % Change |
|---|---|---|---|---|
| Revenue | $19,292 | $13,533 | 43% | |
| Net income – Reported | 6,636 | 4,410 | 50% | |
| Earnings per share – Reported | 7.39 | 4.88 | 51% | |
| Net income – Non-GAAP | 6,771 | 4,806 | 41% | |
| Earnings per share – Non-GAAP | 7.54 | 5.32 | 42% |
CONDENSED CONSOLIDATED BALANCE SHEETS
| $ in millions | December 31, 2025 | December 31, 2024 |
|---|---|---|
| Current assets: | ||
| Cash and cash equivalents | $10,123 | $8,256 |
| Accounts receivable | 7,292 | 5,804 |
| Inventories | 3,256 | 2,905 |
| Other current assets | 1,254 | 1,267 |
| Total current assets | 21,925 | 18,232 |
| Property, plant, and equipment, net | 16,758 | 15,502 |
| Goodwill and other intangible assets | 5,324 | 5,774 |
| Other non-current assets | 2,956 | 3,106 |
| Total assets | $47,963 | $42,614 |
| Current liabilities: | ||
| Accounts payable | $4,525 | $4,119 |
| Accrued expenses | 3,268 | 2,578 |
| Short-term debt | 2,178 | 1,624 |
| Other current liabilities | 1,547 | 1,113 |
| Total current liabilities | 11,518 | 9,434 |
| Long-term debt | 12,194 | 11,336 |
| Other non-current liabilities | 3,076 | 2,960 |
| Total liabilities | 26,788 | 23,730 |
| Shareholders’ equity | 21,175 | 18,884 |
| Total liabilities and equity | $47,963 | $42,614 |